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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX38 All Species: 22.42
Human Site: S994 Identified Species: 37.95
UniProt: Q92620 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92620 NP_054722.2 1227 140503 S994 P K G R E E E S D Q I R E K F
Chimpanzee Pan troglodytes Q7YR39 1044 119631 C839 L A S E K Y S C S E E I L T V
Rhesus Macaque Macaca mulatta XP_001097681 1323 150587 S1090 P K G R E E E S D Q I R E K F
Dog Lupus familis XP_536800 1226 140550 S993 P K G R E E E S D Q I R E K F
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 L1036 M L T I V S M L S V Q N V F Y
Rat Rattus norvegicus Q5XI69 779 88496 Q574 G A P A S W C Q K H W I H W R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025753 1230 141019 S997 P K G R E E E S D Q V R E K F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957170 1258 143711 S1025 P K G R E E E S D Q V R E K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572947 1222 139562 A996 P K G R E D E A D G V R E K F
Honey Bee Apis mellifera XP_001122500 1093 125136 N888 V Y N Q W K A N G Y S S S W C
Nematode Worm Caenorhab. elegans P34498 1131 129405 A904 P K G R E E E A D A K K E K F
Sea Urchin Strong. purpuratus XP_786478 1200 137247 S995 P K G R E E D S D Q A R E K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 I962 I L T M I A M I Q T G N I F Y
Baker's Yeast Sacchar. cerevisiae P15938 1071 121634 F866 S H W C N K H F V Q Y K S L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37 92.2 97.7 N.A. 37.7 22.6 N.A. N.A. 89.8 N.A. 81.3 N.A. 62.3 58.1 55.5 68.4
Protein Similarity: 100 53.7 92.6 99.1 N.A. 55.7 37.3 N.A. N.A. 95.1 N.A. 89.9 N.A. 77.3 72.1 71.3 81
P-Site Identity: 100 0 100 100 N.A. 0 0 N.A. N.A. 93.3 N.A. 93.3 N.A. 73.3 0 73.3 86.6
P-Site Similarity: 100 13.3 100 100 N.A. 6.6 0 N.A. N.A. 100 N.A. 100 N.A. 93.3 20 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 36.1 36.8 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 55 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 8 0 8 8 15 0 8 8 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 8 8 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 8 8 0 58 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 58 50 50 0 0 8 8 0 58 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 15 58 % F
% Gly: 8 0 58 0 0 0 0 0 8 8 8 0 0 0 0 % G
% His: 0 8 0 0 0 0 8 0 0 8 0 0 8 0 0 % H
% Ile: 8 0 0 8 8 0 0 8 0 0 22 15 8 0 0 % I
% Lys: 0 58 0 0 8 15 0 0 8 0 8 15 0 58 0 % K
% Leu: 8 15 0 0 0 0 0 8 0 0 0 0 8 8 0 % L
% Met: 8 0 0 8 0 0 15 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 0 0 8 0 0 0 15 0 0 0 % N
% Pro: 58 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 8 8 50 8 0 0 0 0 % Q
% Arg: 0 0 0 58 0 0 0 0 0 0 0 50 0 0 8 % R
% Ser: 8 0 8 0 8 8 8 43 15 0 8 8 15 0 0 % S
% Thr: 0 0 15 0 0 0 0 0 0 8 0 0 0 8 0 % T
% Val: 8 0 0 0 8 0 0 0 8 8 22 0 8 0 15 % V
% Trp: 0 0 8 0 8 8 0 0 0 0 8 0 0 15 0 % W
% Tyr: 0 8 0 0 0 8 0 0 0 8 8 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _